Hemophagocytic lymphohistiocytosis (HLH) is a disease that can affect both children and adults. HLH can be categorized as primary or secondary. Secondary HLH (sHLH) may be secondary to various viral infections. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus infection is a pandemic with multi-system involvement. HLH in COVID-19 positive patients is a recognized entity. However, in post-COVID-19 patients who have recovered and are negative by serological tests and reverse transcription-polymerase chain reaction test may present with sHLH due to dysregulation of the immune system. We highlight this unusual finding of post-COVID-19 sHLH in two cases, who were diagnosed by the new revised H-score.
【저자키워드】 COVID-19, SARS-CoV-2, immune system, Bone marrow, secondary hemophagocytic lymphohistiocytosis, 【초록키워드】 serological test, coronavirus, pandemic, children, viral infections, Adults, virus infection, disease, HLH, dysregulation, acute respiratory syndrome, sHLH, Affect, secondary, highlight, diagnosed, COVID-19 positive patient, post-COVID-19 patient, 【제목키워드】 hemophagocytic lymphohistiocytosis, report, secondary,