The world is experiencing the COVID-19 outbreak and there are no evidence-based treatment strategies available for immunocompromised patients. COVID-19 is a novel beta coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with cancer are more susceptible to infection than individuals without cancer due to their impaired humoral and cellular immune function caused by the malignancy itself and chemotherapy. We present three cases of cancer patients with hypogammaglobulinemia with varying clinical outcomes associated with infection. These include one mantle cell lymphoma patient with recurrent respiratory infection requiring intravenous immunoglobulin (IVIG) support and two multiple myeloma patients with continued viral shedding.
【저자키워드】 COVID 19, Multiple myeloma, lymphoma, Hypogammaglobulinemia, Intravenous immunoglobulin (IVIG), mantle cell lymphoma, 【초록키워드】 COVID-19, SARS-CoV-2, Intravenous immunoglobulin, coronavirus, Cancer, Infection, viral shedding, Immunocompromised patients, Clinical outcome, Chemotherapy, respiratory infection, COVID-19 outbreak, Patient, treatment strategy, malignancy, humoral, cancer patient, Support, acute respiratory syndrome, beta coronavirus, susceptible, caused, include, cellular immune function, individuals without cancer, mantle cell, 【제목키워드】 COVID-19,