Mass vaccination against coronavirus disease 19 (COVID-19) has effectively controlled the pandemic and has been remarkably effective and safe. Reports of a few adverse events have been reported after post-marketing surveillance. We present a rare case of multiple sclerosis (MS) relapse in a female who presented with fatigue, involuntary eye movements, and numbness; autoimmunity following the COVID-19 vaccine has also been described. She was diagnosed with MS six years back and was in remission. She received her COVID-19 vaccine 18 days ago. Her clinical and radiological features confirmed the MS relapse. Her serology for COVID-19 immunoglobulin G (IgG) and IgM was positive, and she was managed with intravenous methylprednisolone and symptomatic management. Our case provides a possible association of vaccine-associated MS relapse; however, more evidence is warranted from future studies.
【저자키워드】 COVID-19 vaccine, multiple sclerosis, SARS-CoV-2 pandemic, mRNA-based vaccine, multiple sclerosis flare-up, 【초록키워드】 COVID-19, coronavirus disease, IgG, IgM, Autoimmunity, pandemic, fatigue, serology, Immunoglobulin, Surveillance, symptomatic, management, adverse event, female, association, Evidence, Safe, mass vaccination, report, positive, intravenous methylprednisolone, effective, described, reported, diagnosed, provide, effectively controlled, radiological feature, 【제목키워드】 COVID-19, review, literature, Relapse, report, Multiple, sclerosis,