Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging human coronavirus responsible for coronavirus disease 2019 (COVID-19), a predominantly respiratory disease that has become a global pandemic. Millions of people worldwide are suffering from COVID-19, and hundreds of thousands of those infected have died. Nevertheless, many more people who have been infected with SARS-CoV-2 are asymptomatic or suffer a mild disease characterized by dry cough and mild fever. This new pandemic poses a threat to public health on a global scale, and an intervention to prevent continued spread of SARS-CoV-2 virus is of the utmost importance. To assess preventive and therapeutic strategies, it is imperative to understand the pathogenesis and immune response against SARS-CoV-2. In this review, we concentrate on the protective adaptive immune response elicited by this novel coronavirus as well as requirements for a successful vaccine inducing optimal protection.
【저자키워드】 COVID-19, SARS-CoV-2, Vaccines, Neutralizing antibodies, T-cell immunity, 【초록키워드】 coronavirus disease, public health, Vaccine, coronavirus, immune response, pandemic, Pathogenesis, SARS-CoV-2 virus, Intervention, Novel coronavirus, global pandemic, Spread, Asymptomatic, Fever, Respiratory disease, Therapeutic strategies, Mild, Adaptive immune response, disease, Protective, acute respiratory syndrome, dry cough, Prevent, responsible, died, characterized, imperative, elicited, infected with SARS-CoV-2, 【제목키워드】 respiratory, Against,