Neurological diseases related to coronavirus disease-2019 (COVID-19) are increasingly reported. We report here three cases that presented with subtle neurologic findings manifesting within a range of 15 days to four months after their COVID-19 diagnoses. Magnetic resonance imaging showed acute multifocal periventricular and subcortical demyelinating lesions. Some of the lesions showed contrast enhancement and diffusion restriction. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) PCR was found in the cerebrospinal fluid of just one patient. All patients received intravenous methylprednisolone therapy. In this report, we aim to discuss the aspects of possible COVID-19-related demyelination that support a diagnosis of multiple sclerosis (MS) or acute disseminated encephalomyelitis (ADEM).
【저자키워드】 COVID-19, multiple sclerosis, ADEM, Demyelinating disease, demiyelination, 【초록키워드】 SARS-CoV-2, coronavirus, therapy, Diagnosis, PCR, Patient, cerebrospinal fluid, disease, Demyelination, Support, lesion, acute respiratory syndrome, diagnoses, lesions, intravenous methylprednisolone, diffusion, neurologic, reported, increasingly, subcortical, 【제목키워드】 demyelinating, concurrent, System, nervous,