While the majority of pediatric coronavirus disease 2019 (COVID-19) cases have not been critical, occurrences of a multisystem inflammatory syndrome in children (MIS-C) have been emerging as the pandemic progresses. Herein, we report our experience with a pediatric COVID-19 case that presented with shock and multisystem inflammation. Our patient notably had multiple negative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcription polymerase chain reaction (RT-PCR) assays but tested positive for SARS-CoV-2 IgG antibody. This case not only highlights the utility of SARS-CoV-2 IgG in the diagnosis of COVID-19 when RT-PCR is negative but suggests MIS-C may be a post-infectious immune-mediated process.
【저자키워드】 COVID-19, SARS-CoV-2, Inflammation, pediatric, MIS-C, multisystem, 【초록키워드】 coronavirus disease, coronavirus, children, RT-PCR, Shock, SARS-CoV-2 IgG antibody, Patient, reverse transcription, utility, Critical, SARS-CoV-2 IgG, Immune-mediated, Inflammatory, acute respiratory syndrome, COVID-19 case, syndrome, positive, while, highlight, polymerase chain, Occurrence, tested, majority, diagnosis of COVID-19, pandemic progresses,