The possibilities of coronavirus disease 2019 (COVID-19) to present with atypical manifestations have reported. Information of COVID-19 atypical signs and symptoms is still emerging globally. One of these presentations is persistent hiccups. One of the hypotheses is that COVID-19 has been linked to several neurological manifestations and effects. Some observations noticed phrenic nerve paralysis after COVID-19 infection leading to pulmonary failure. We report one case of COVID-19-positive patient where he presented with persistent hiccups. Many predisposing factors might lead to the development of hiccups in COVID-19 infection such as a history of smoking, phrenic and vagus nerve damage or irritation, high inflammatory markers, lower lobe pneumonia, ground-glass-like appearance on x-rays. We hypothesize that hiccups are the first sign of serious deterioration of patients with COVID-19 and such patients are at high risk of developing kidney injury and intubation.
【저자키워드】 COVID-19 presentation, hiccups, covid-19 hicupps, persistent hiccups, intractable hiccups, 【초록키워드】 COVID-19, coronavirus disease, Pneumonia, inflammatory markers, intubation, Symptom, smoking, Kidney injury, Deterioration, COVID-19 infection, Patient, Atypical, manifestation, high risk, nerve damage, observation, pulmonary failure, Factor, paralysis, lower lobe, neurological manifestation, Effects, reported, hypothese, hiccup, patients with COVID-19, phrenic, 【제목키워드】 Saudi Arabia, Jeddah, persistent, center,