Vaccine-induced thrombotic thrombocytopenia is a life-threatening prothrombotic syndrome that has been associated with two adenoviral vector-based coronavirus disease 2019 (COVID-19) vaccines. Although it remains a rare disorder with relatively low incidence, awareness of this condition is crucial given the ongoing vaccination programs of millions around the world. In this case series, we report four cases of vaccine-induced thrombotic thrombocytopenia, diagnosed at Queen Alexandra Hospital, Portsmouth, United Kingdom. We also review the mechanism of this syndrome, its clinical presentation, diagnosis, and course of treatment with emphasis on the role of therapeutic plasma exchange.
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【저자키워드】 COVID-19, corona virus disease 2019, Ad26.COV2.S vaccine, vaccine-induced thrombotic thrombocytopenia (VITT), covid-19 vaccine complication, chadox1 cov-19 vaccine, 【초록키워드】 Treatment, coronavirus disease, vaccination, Vaccines, Diagnosis, Case series, incidence, United Kingdom, mechanism, Therapeutic plasma exchange, syndrome, thrombotic, life-threatening, disorder, prothrombotic syndrome, Course, diagnosed, Alexandra, 【제목키워드】 Sery,
【저자키워드】 COVID-19, corona virus disease 2019, Ad26.COV2.S vaccine, vaccine-induced thrombotic thrombocytopenia (VITT), covid-19 vaccine complication, chadox1 cov-19 vaccine, 【초록키워드】 Treatment, coronavirus disease, vaccination, Vaccines, Diagnosis, Case series, incidence, United Kingdom, mechanism, Therapeutic plasma exchange, syndrome, thrombotic, life-threatening, disorder, prothrombotic syndrome, Course, diagnosed, Alexandra, 【제목키워드】 Sery,