Here, we report a case of acute endothelial graft rejection following coronavirus disease 2019 (COVID-19). A 57-year-old woman who underwent therapeutic penetrating keratoplasty for a perforated infectious corneal ulcer in her right eye developed severe acute respiratory syndrome coronavirus 2 infection, which required intensive care and treatment with steroids. Acute endothelial graft rejection was seen at three weeks postoperatively and managed with high-dose corticosteroids. Despite standard therapy, secondary graft failure was observed. Immune dysregulation associated with COVID-19 may be a significant cause of acute endothelial graft rejection among keratoplasty patients with COVID-19.
All Keywords
【저자키워드】 COVID-19, SARS-CoV-2, acute endothelial graft rejection, therapeutic penetrating keratoplasty, corneal ulcer, 【초록키워드】 Treatment, coronavirus disease, coronavirus, Corticosteroids, intensive care, Steroids, therapeutic, Standard therapy, dysregulation, High-dose, endothelial, acute respiratory syndrome, rejection, Penetrating, Corneal, required, patients with COVID-19, with COVID-19, 【제목키워드】 Graft,
【저자키워드】 COVID-19, SARS-CoV-2, acute endothelial graft rejection, therapeutic penetrating keratoplasty, corneal ulcer, 【초록키워드】 Treatment, coronavirus disease, coronavirus, Corticosteroids, intensive care, Steroids, therapeutic, Standard therapy, dysregulation, High-dose, endothelial, acute respiratory syndrome, rejection, Penetrating, Corneal, required, patients with COVID-19, with COVID-19, 【제목키워드】 Graft,