Since the 2019 novel coronavirus outbreak began in Wuhan, China, diagnostic methods in the field of molecular biology have been developing faster than ever under the vigilant eye of world’s research community. Unfortunately, the medical community was not prepared for testing such large volumes or ranges of biological materials, whether blood samples for antibody immunological testing, or salivary/swab samples for real-time PCR. For this reason, many medical diagnostic laboratories have made the switch to working in the field of molecular biology, and research undertaken to speed up the flow of samples through laboratory. The aim of this narrative review is to evaluate the current literature on laboratory techniques for the diagnosis of SARS-CoV-2 infection available on pubmed.gov, Google Scholar, and according to the writers’ knowledge and experience of the laboratory medicine. It assesses the available information in the field of molecular biology by comparing real-time PCR, LAMP technique, RNA sequencing, and immunological diagnostics, and examines the newest techniques along with their limitations for use in SARS-CoV-2 diagnostics.
【저자키워드】 COVID-19, SARS-CoV-2, real-time polymerase chain reaction, LAMP assay, 【초록키워드】 Molecular biology, antibody, knowledge, Infection, diagnostic, diagnostics, Laboratory, 2019 novel coronavirus, Real-time PCR, outbreak, RNA sequencing, Research, Community, information, Diagnostic method, Google Scholar, Volume, blood sample, limitation, immunological, Wuhan, China, evaluate, faster, diagnosis of SARS-CoV-2, 【제목키워드】 Medicine, lesson, role,