Since the outbreak of the new coronavirus, healthcare systems around the world have witnessed not only COVID-19 symptoms but also long-term complications of the aforementioned, including neurological problems. We report a clinical case of an adult patient with bilateral facial nerve palsy and progressive ascending paresis of the limbs after contracting the novel coronavirus (COVID-19). Additionally, the systematic review aimed to identify and summarize specific clinical features, outcomes and complications of the studies focusing on bilateral facial diplegia as a sequela of COVID-19 infection. The total number of analyzed patients was 15. Only one patient was diagnosed with isolated bilateral palsy; the rest had Guillain-Barré Syndrome (GBS). With one exception, all the presented cases had favorable outcomes, with facial palsy recovery from slight to almost complete. In patients with a confirmed COVID-19 diagnosis, bilateral facial palsy may be an isolated symptom as well as a variant of GBS. Symptoms of cranial nerve damage during a COVID-19 infection may explain the appearance of facial nerve damage. In order to clarify the spectrum of neurological manifestations and a causal relation between SARS-CoV-2, COVID-19 vaccination and neurological symptoms, direct attention towards the study of this virus is crucial. It seems reasonable to recognize human coronavirus as another potential GBS trigger.
【저자키워드】 COVID-19, SARS-CoV-2, COVID-19 vaccination, Guillain-Barré syndrome, bell’s palsy, peripheral nervous system disease, peripheral facial nerve palsy, 【초록키워드】 coronavirus, variant, systematic review, Symptom, outcome, virus, Clinical features, Novel coronavirus, outcomes, COVID-19 infection, outbreak, Patient, COVID-19 diagnosis, Complication, Neurological symptoms, New coronavirus, Healthcare system, COVID-19 symptom, nerve damage, facial nerve palsy, neurological problems, Complete, neurological manifestation, limb, analyzed, identify, diagnosed, recognize, explain, cranial, facial, 【제목키워드】 review, literature, manifestation, systemic, report,