Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic recently. The prevalence and persistence of antibodies following a peak SARS-CoV-2 infection provides insights into the potential for some level of population immunity. In June 2020, we succeeded in testing almost half of the population of an Austrian town with a higher incidence of COVID-19 infection. We performed a follow-up study to reassess the prevalence of SARS-CoV-2-specific IgA and IgG antibodies with 68 participants of the previous study. We found that the prevalence of IgG or IgA antibodies remained remarkably stable, with 84% of our cohort prevailing SARS-CoV-2-specific antibodies (only a slight decrease from 93% 4 months before). In most patients with confirmed COVID-19 seroconversion potentially provides immunity to reinfection. Our results suggest a stable antibody response observed for at least 6 months post-infection with implications for developing strategies for testing and protecting the population.
【저자키워드】 COVID-19, SARS-CoV-2, antibody, Population, serotype, 【초록키워드】 IgG, coronavirus, Immunity, SARS-COV-2 infection, Antibody Response, Infection, global pandemic, Prevalence, Reinfection, Cohort, Seroconversion, IgG antibody, IgA, persistence, Patient, population immunity, follow-up study, Post-infection, acute respiratory syndrome, SARS-CoV-2-specific antibody, participant, implication, decrease, performed, caused, remained, provide, IgA antibody, incidence of COVID-19, 【제목키워드】 response,