Angiotensin converting enzyme 2 (ACE 2 ) seems to be a central actor in the pathophysiology of SARS-Cov-2 infection. First, it acts as the receptor for the virus and permits its attachment to cells expressing ACE 2 . Second, the relative deficiency of ACE 2 during infection could be linked to several clinical features encountered during the disease, like ARDS and coagulation abnormalities. This study explores the strong link between ACE 2 and the majority of risk factors for the severe evolution of COVID-19. It seems that all these risks factors are linked to an increased level of ACE 2 and/or imbalance in ACE/ACE 2 .
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【저자키워드】 COVID-19 pandemic, Lung injury, pathophysiology, SARS – CoV – 2, Angiotensin-converting enzyme, bradykinin - analogs and derivatives, 【초록키워드】 COVID-19, Evolution, ARDS, Infection, risk, risk factor, virus, angiotensin converting enzyme, Coagulation, receptor, clinical feature, ACE, deficiency, Factor, Abnormalities, second, Cell, the disease, majority, expressing, 【제목키워드】 ACE,
【저자키워드】 COVID-19 pandemic, Lung injury, pathophysiology, SARS – CoV – 2, Angiotensin-converting enzyme, bradykinin - analogs and derivatives, 【초록키워드】 COVID-19, Evolution, ARDS, Infection, risk, risk factor, virus, angiotensin converting enzyme, Coagulation, receptor, clinical feature, ACE, deficiency, Factor, Abnormalities, second, Cell, the disease, majority, expressing, 【제목키워드】 ACE,