Coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally and rapidly developed into a worldwide pandemic. The sudden outburst and rapid dissemination of SARS-CoV-2, with overwhelming public health and economic burdens, highlight an urgent need to develop effective strategies for the diagnosis and treatment of infected patients. In this review, we focus on the current advances in the diagnostics and treatment for SARS-CoV-2 infection. Notably, we also summarize some antineoplastic drugs repurposed for COVID-19 treatment and address the diagnostic and therapeutic challenges for oncologists to manage cancer patients in this COVID-19 era. In addition, we emphasize the importance of organoid technology as a valuable experimental virology platform to better understand the pathogenesis of COVID-19 and assist rapid screening of drugs against COVID-19.
【저자키워드】 COVID-19, Treatment, SARS-CoV-2, diagnostics, Organoid, cancer patient, 【초록키워드】 public health, Coronavirus disease 2019, coronavirus, SARS-COV-2 infection, diagnostic, Diagnosis, drug, Spread, therapeutic, dissemination, platform, acute respiratory syndrome, infected patients, worldwide pandemic, pathogenesis of COVID-19, oncologist, highlight, develop, caused, addition, assist, antineoplastic drug, effective strategy, 【제목키워드】 Impact, application, advance,