Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly infectious virus with overwhelming demand on healthcare systems, which require advanced predictive analytics to strategize COVID-19 management in a more effective and efficient manner. We analyzed clinical data of 2017 COVID-19 cases reported in the Dubai health authority and developed predictive models to predict the patient’s length of hospital stay and risk of death. A decision tree (DT) model to predict COVID-19 length of stay was developed based on patient clinical information. The model showed very good performance with a coefficient of determination R 2 of 49.8% and a median absolute deviation of 2.85 days. Furthermore, another DT-based model was constructed to predict COVID-19 risk of death. The model showed excellent performance with sensitivity and specificity of 96.5 and 87.8%, respectively, and overall prediction accuracy of 96%. Further validation using unsupervised learning methods showed similar separation patterns, and a receiver operator characteristic approach suggested stable and robust DT model performance. The results show that a high risk of death of 78.2% is indicated for intubated COVID-19 patients who have not used anticoagulant medications. Fortunately, intubated patients who are using anticoagulant and dexamethasone medications with an international normalized ratio of <1.69 have zero risk of death from COVID-19. In conclusion, we constructed artificial intelligence–based models to accurately predict the length of hospital stay and risk of death in COVID-19 cases. These smart models will arm physicians on the front line to enhance management strategies to save lives.
【저자키워드】 COVID-19, artificial intelligence, Length of stay, Predictive analytics, risk of death, 【초록키워드】 Dexamethasone, SARS-CoV-2, coronavirus, medications, Dubai, Predictive model, Accuracy, Sensitivity and specificity, management, International, Patient, death, medication, predict, Anticoagulant, Infectious virus, COVID-19 cases, Hospital stay, high risk, Predictive, Health authority, Healthcare systems, acute respiratory syndrome, Clinical data, COVID-19 case, clinical information, physician, deviation, approach, effective, Receiver operator characteristic, robust, ENhance, analyzed, reported, indicated, the patient, median, suggested, R 2, intubated COVID-19 patient, intubated patient, normalized, 【제목키워드】 prediction, artificial, modeling, Length,