Because severe coronavirus disease 2019 (COVID-19) affects the respiratory system and develops into respiratory failure, patients with pre-existing chronic lung disorders, such as idiopathic pulmonary fibrosis (IPF), are thought to be at high risk of death. Patients with IPF often suffer from a lethal complication, acute exacerbation (AE), a significant part of which is assumed to be triggered by respiratory viral infection. However, whether mild to moderate COVID-19 can trigger AE in patients with IPF remains unknown. This is the case report of a 60-year-old man with a 4-year history of IPF who successfully recovered from moderate COVID-19 but subsequently developed more severe respiratory failure, which was considered to be a COVID-19-triggered acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF). It is important to be aware of the risk of AE-IPF after COVID-19 and to properly manage this deadly complication of IPF. Recent literature reporting cases with chronic interstitial lung diseases which developed respiratory failure by complications with COVID-19 is also reviewed and discussed.
【저자키워드】 COVID-19, viral infection, Idiopathic pulmonary fibrosis, acute exacerbation, high resolution CT scan, 【초록키워드】 Respiratory failure, pulmonary fibrosis, severe respiratory failure, risk, Interstitial lung disease, Case report, Moderate COVID-19, Patient, death, Complication, Mild, Respiratory system, respiratory viral infection, IPF, high risk, severe coronavirus disease, lung disorders, Affect, recent, thought, develop, triggered, assumed, patients with IPF, with COVID-19, 【제목키워드】 review, clinical, respiratory, literature, IPF, Exacerbation, report, entity,