Aim: Despite the similarities in the pathogenesis of the beta coronaviruses, the precise infective mechanisms of SARS-CoV-2 remain unclear. Objective: In this review, we aim to focus on the proposed theories behind the pathogenesis of SARS-CoV-2 and highlight the clinical complications related to coronavirus disease 2019 (COVID-19). Methods: We conducted a literature search in Pubmed, Scopus and Google Scholar for the relevant articles regarding clinical complications and pathogenesis of COVID-19. Results: Related articles were included and discussed. Conclusion: Respiratory system and the lungs are the most commonly involved sites of COVID-19 infection. Cardiovascular, liver, kidneys, gastrointestinal and central nervous systems are involved with different frequencies and degrees of severity.
【저자키워드】 SARS-CoV-2, Coronavirus disease 2019, Pathogenesis, clinical complications, 【초록키워드】 COVID-19, coronavirus disease, severity, lung, cardiovascular, COVID-19 infection, Central nervous system, respiratory, liver, mechanism, Frequency, similarity, Google Scholar, Beta coronaviruses, kidneys, pathogenesis of COVID-19, article, infective, pathogenesis of SARS-CoV-2, highlight, clinical complication, involved, conducted, 【제목키워드】 COVID-19, coronavirus disease, Complication,