Recent reports have shown that the renin angiotensin system (RAS) plays an important role in the Coronavirus disease 2019 (COVID-19) because the angiotensin converting enzyme 2 is the receptor for the severe acute respiratory syndrome coronavirus 2. In addition, the balance of RAS components can be involved in the pathogenesis and progression of COVID-19, especially in patients with metabolic and cardiovascular diseases. On the other hand, physical exercise is effective to prevent and to counteract the consequences of such diseases and one of the biological mediators of the exercise adaptation is the RAS. This review was designed to highlight the connection between COVID-19 and RAS, and to discuss the role of the RAS as a mediator of the benefits of physical exercise in COVID-19 pandemic.
【저자키워드】 Treatment, coronavirus, angiotensin converting enzyme 2, molecular mechanism, Exercise training, cardiometabolic diseases, 【초록키워드】 COVID-19, Coronavirus disease 2019, Pathogenesis, COVID-19 pandemic, cardiovascular diseases, progression, RAS, Patient, receptor, disease, connection, acute respiratory syndrome, enzyme, component, recent, Prevent, physical, effective, benefit, consequence, highlight, shown, involved, addition, 【제목키워드】 COVID-19, exercise, angiotensin, Renin,