V/P SPECT from 4 consecutive patients with COVID-19 suggests that ventilation and perfusion images may be applied to diagnose or exclude pulmonary embolism, verify nonsegmental diversion of perfusion from the ventilated areas (dead space ventilation) that may represent inflammation of the pulmonary vasculature, detect the reversed mismatch of poor ventilation and better preserved perfusion (shunt perfusion) in bilateral pulmonary inflammation and indicate redistribution of lung perfusion (antigravitational hyperperfusion) due to cardiac congestion. V/P mismatch and reversed mismatch may be extensive enough to diminish dramatically preserved matching ventilation/perfusion and to induce severe hypoxemia in COVID-19.
【저자키워드】 COVID-19, SARS-CoV-2, Ventilation, Pulmonary embolism, Perfusion, SPECT, 【초록키워드】 Inflammation, lung, pulmonary inflammation, vasculature, diagnose, Shunt, Ventilated, severe hypoxemia, dead, detect, induce, reversed, consecutive patient, preserved, ventilation/perfusion, with COVID-19, 【제목키워드】 pulmonary, assessment, function, report, with COVID-19,