The total number of COVID-19 positive cases in Latvia has escalated rapidly since October 2020, peaking in late December 2020 and early January 2021. Children generally develop COVID-19 more mildly than adults; however, it can be complicated by multisystem inflammatory syndrome in children (MIS-C). This case study aims were to assess demographic characteristics and the underlying medical conditions, and clinical, investigative and treatment data among 13 MIS-C patients using electronic medical records. All 13 had acute illness or contact with someone who was COVID-19 positive two to six weeks before MIS-C onset. Only five of the 13 were symptomatic during the acute COVID-19 phase. The median age was 8.8 years; 11/13 patients were male, 10/13 had been previously healthy, and all 13 patients tested positive for SARS-CoV-2 by RT-PCR or antibody testing. The most commonly involved organ systems were the gastrointestinal (13/13), hematologic (13/13), cardiovascular (13/13), skin and mucosa (13/13), and respiratory (12/13) ones. The median hospital stay was 13 (interquartile range, 11 to 18) days; 7/13 patients received intensive care, 6/13 oxygen support, and 5/13 received inotropic support. No deaths occurred. During the current pandemic, every child with a fever should have a clearly defined epidemiological history of COVID-19, a careful clinical assessment of possible multiple organ-system involvement, with a special focus on children with severe abdominal pain and/or skin and mucocutaneous lesions.
【저자키워드】 COVID-19, SARS-CoV-2, multisystem inflammatory syndrome in children (MIS-C), 【초록키워드】 Treatment, Antibody testing, pandemic, intensive care, children, abdominal pain, RT-PCR, MIS-C, symptomatic, Fever, male, Patient, death, electronic medical records, Inflammatory, Contact, Medical conditions, mucosa, Hospital stay, demographic characteristics, organ system, Support, interquartile range, epidemiological history, median age, lesions, syndrome, acute COVID-19, oxygen support, hematologic, positive, acute illness, Latvia, FIVE, peaking, defined, tested, develop, occurred, involved, healthy, median, 【제목키워드】 MIS-C, Latvia, Sery, the SARS-CoV-2,