Coronavirus disease 2019 (COVID-19) is a highly contagious, infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in late 2019 in Wuhan China. A year after the World Health Organization declared COVID-19 a global pandemic, over 215 million confirmed cases and approximately 5 million deaths have been reported worldwide. In this multidisciplinary review, we summarize important insights for COVID-19, ranging from its origin, pathology, epidemiology, to clinical manifestations and treatment. More importantly, we also highlight the foundational connection between genetics and the development of personalized medicine and how these aspects have an impact on disease treatment and management in the dynamic landscape of this pandemic.
【저자키워드】 COVID-19, SARS-CoV-2, coronavirus, targeted therapy, COVID epidemiology, COVID treatment, COVID origin, 【초록키워드】 Treatment, pathology, Coronavirus disease 2019, pandemic, Epidemiology, Infectious disease, genetics, global pandemic, China, management, Personalized medicine, Wuhan, death, disease, clinical manifestation, World Health Organization, confirmed case, connection, acute respiratory syndrome, contagious, highlight, caused, reported, 【제목키워드】 landscape, insight, Changing,