Background: The COVID-19 outbreak, which was first reported in Wuhan, China, in December 2019, began to spread throughout the world, and now involves over 200 countries. Methods: A total of 37 overseas young and middle-aged people, who tested as SARS-CoV-2 positive upon their return to Shanghai, were enrolled for an analysis of their clinical symptoms, blood routine indexes, and lung CT images. Results: The clinical symptoms were characterized by fever (51.4%), dry cough (13.5%), expectoration (27.0%), hypodynamia (21.6%), pharyngalia (10.8%), pharynoxerosis (8.1%), rhinobyon (13.5%), rhinorrhea (8.1%), muscular soreness (16.2%), and diarrhea (2.7%). In 16.2% of cases, no symptoms were reported. Fever was the most common symptom (51.40%). The pneumonic changes referred to the latticed ground glass imaging and similar white lung imaging accompanied by consolidated shadows. The rate of pneumonia was high (81.10%). We found that the exclusive percent of eosinophils was abnormally low. By analyzing the correlation of eosinophils, fever, and pneumonia, we found that the percentage of eosinophils was low in the COVID-19 patients afflicted with fever or pneumonia ( P < 0.01). Additionally, pneumonia and fever were negatively correlated with the percentage of eosinophils and eosinophils/neutrophils ratio ( P < 0.01, respectively), but not associated with pneumonia severity ( P > 0.05). Fever was not correlated with pneumonia ( P > 0.05). Conclusion: A low percentage of eosinophils may be considered as a biomarker of pneumonia of COVID-19, but not as a biomarker of pneumonia severity.
【저자키워드】 COVID-19, SARS-CoV-2, Clinical features, Computed tomography, Viral pneumonia, blood index, 【초록키워드】 Biomarker, Clinical symptoms, Pneumonia, severity, Symptom, diarrhea, eosinophil, Spread, COVID-19 outbreak, eosinophils, Fever, ground glass, Shanghai, correlation, change, Analysis, COVID-19 patient, Lung imaging, Lung CT, no symptom, clinical symptom, dry cough, Blood routine, rhinorrhea, positive, Wuhan, China, enrolled, tested, reported, characterized, correlated, accompanied, muscular, not correlated, 【제목키워드】 clinical, Shanghai, Chinese,