The antigen rapid diagnostic test (Ag-RDT) is an immunodiagnostic test that detects the presence of viral proteins (antigens) expressed by the COVID-19 virus in a sample from a patient’s respiratory tract. This study focused on evaluating the performance of self-conduct buccal and nasal swabs RTK-antigen test compared to nasopharyngeal swab RTK-based COVID-19 diagnostic assays, Panbio™ COVID-19 Ag Rapid Test Device (Nasopharyngeal) (Abbott Rapid Diagnostics Jena GmbH, Jena, Germany) used in hospitals for first-line screening. The sensitivity and specificity of the paired RTK-Ag test in detecting the an-tigen were calculated at 96.4% and 100%, respectively. Fisher exact tests showed the association between nasopharyngeal swabs RTK-Ag assay and buccal-nasal swabs RTK-Ag from Prodetect TM is significant ( p -values < 0.001). The result showed that a self-conducted buccal and nasal RTK-antigen rapid test by the patients is comparable to the results obtained from a rapid test device conducted by trained medical personnel using a nasopharyngeal swab.
【저자키워드】 SARS-CoV-2, performance validation, rapid self-conduct RTK-antigen test, 【초록키워드】 COVID-19, hospital, Test, nasal, Antigen, Nasopharyngeal swab, Rapid test, Sensitivity and specificity, Rapid diagnostic test, Germany, Rapid, COVID-19 virus, antigens, respiratory tract, Swab, nasal swab, Ag-RDT, association, Device, Abbott, Viral protein, P -value, Fisher exact test, COVID-19 diagnostic assays, detect, the patient, conducted, calculated, expressed, comparable, 【제목키워드】 COVID-19, validation, performance, Buccal,