The current rapid spread of the novel coronavirus (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) calls for a rapid response from the research community. Lithium is widely used to treat bipolar disorder, but has been shown to exhibit antiviral activity. This brief review took a systematic approach to identify six in vitro studies reporting on the influence of lithium on coronaviral infections. We propose mechanistic investigation of the influence of lithium – alone and with chloroquine – on the SARS-CoV-2 infection.
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【저자키워드】 Apoptosis, coronavirus, Antiviral, 2019-nCoV, Wuhan, lithium, Coronaviridae, GSK-3β, lithium carbonate, lithium orotate, glycogen synthase kinase 3-beta, 【초록키워드】 COVID-19, coronavirus disease, SARS-CoV-2, Chloroquine, Infection, antiviral activity, Novel coronavirus, Spread, infections, Research, Community, rapid response, in vitro study, treat, disorder, Coronaviral, approach, shown, identify, the SARS-CoV-2, 【제목키워드】 infections, Coronaviral,
【저자키워드】 Apoptosis, coronavirus, Antiviral, 2019-nCoV, Wuhan, lithium, Coronaviridae, GSK-3β, lithium carbonate, lithium orotate, glycogen synthase kinase 3-beta, 【초록키워드】 COVID-19, coronavirus disease, SARS-CoV-2, Chloroquine, Infection, antiviral activity, Novel coronavirus, Spread, infections, Research, Community, rapid response, in vitro study, treat, disorder, Coronaviral, approach, shown, identify, the SARS-CoV-2, 【제목키워드】 infections, Coronaviral,