Background COVID-19 infection may cause severe respiratory distress and is associated with increased morbidity and mortality. Impaired cardiac function and/or pre-existing cardiovascular disease may be associated with poor prognosis. In the present study, we report a comprehensive cardiovascular characterization in the first consecutive collective of patients that was admitted and treated at the University Hospital of Tübingen, Germany. Methods 123 consecutive patients with COVID-19 were included. Routine blood sampling, transthoracic echocardiography and electrocardiography were performed at hospital admission. Results We found that impaired left-ventricular and right-ventricular function as well as tricuspid regurgitation > grade 1 were significantly associated with higher mortality. Furthermore, elevated levels of myocardial distress markers (troponin-I and NT pro-BNP) were associated with poor prognosis in this patient collective. Conclusion Impaired cardiac function is associated with poor prognosis in COVID-19 positive patients. Consequently, treatment of these patients should include careful guideline-conform cardiovascular evaluation and treatment. Thus, formation of a competent Cardio-COVID-19 team may represent a major clinical measure to optimize therapy of cardiovascular patients during this pandemic.
【저자키워드】 COVID-19, Prognosis, cardiovascular disease, heart failure, cardiac function, 【초록키워드】 Treatment, pandemic, therapy, Mortality, COVID-19 infection, Germany, Patient, Electrocardiography, Hospital admission, morbidity and mortality, university, Blood, marker, distress, impaired cardiac function, poor prognosis, Severe respiratory distress, Tübingen, routine, COVID-19 positive patients, Myocardial, tricuspid, Result, performed, significantly, include, elevated, treated, competent, consecutive patient, NT pro-BNP, with COVID-19, 【제목키워드】 Mortality, Infection, Patient, impaired cardiac function, acute COVID-19,