Highlights • Structural biology plays a vital role in SARS-CoV-2 vaccine and treatment. • High-resolution structures of SARS-CoV-2 proteins and complexes have been obtained. • In situ structures of SARS-CoV-2 virus and its assembly are visualized by cryoET. The SARS-CoV-2 pandemic that struck in 2019 has left the world crippled with hundreds of millions of cases and millions of people dead. During this time, we have seen unprecedented support and collaboration amongst scientists to respond to this deadly disease. Advances in the field of structural biology, in particular cryoEM and cryo-electron tomography, have allowed unprecedented structural analysis of SARS-CoV-2. Here, we review the structural work on the SARS-CoV-2 virus and viral components, as well as its cellular assembly process, highlighting some important structural findings that have made significant impact on the protection from and treatment of emerging viral infections.
【초록키워드】 Treatment, Structure, SARS-CoV-2, structural biology, SARS-CoV-2 pandemic, tomography, SARS-CoV-2 virus, viral infections, SARS-CoV-2 vaccine, disease, cellular, Structural analysis, Support, components, advance, SARS-CoV-2 protein, dead, complexes, respond, highlighting, the SARS-CoV-2 virus, 【제목키워드】 the SARS-CoV-2 virus,