As of 23 April 2021, the outbreak of COVID-19 claimed around 150 million confirmed cases with over 3 million deaths worldwide. Yet, an even more serious but silent pandemic, that of antimicrobial resistance (AMR), is likely complicating the outcome of COVID-19 patients. This study discusses the current knowledge on the emergence of the SARS-CoV-2 and highlights the likely contribution of the COVID-19 pandemic on the escalation of AMR. COVID-19 engenders extensive antibiotic overuse and misuse, and will undoubtedly and substantially increase AMR rates worldwide. Amid the expanding COVID-19 pandemic, policymakers should consider the hidden threat of AMR much more, which may well be enhanced through improper use of antibiotics to treat patients with severe COVID-19 infection. Lay abstract Antimicrobial resistance (AMR) is a natural phenomenon that allows microorganisms to resist to the action of antimicrobial medicines that were previously active against them and cured the infection. AMR is caused by the appropriate and inappropriate use of antimicrobial medicines. The occurrence of the COVID-19 pandemic engenders extensive antimicrobial use that is likely to aggravated the AMR pandemic. This paper discusses the current knowledge on the SARS-CoV-2, and underscores the contribution of the COVID-19 pandemic on the escalation of AMR. Beyond the expanding COVID-19 pandemic, the hidden threat of AMR should also be considered by the decision-makers.
【저자키워드】 SARS-CoV-2, COVID-19 pandemic, antimicrobial resistance, COVID-19 vaccines, Antimicrobial stewardship, 【초록키워드】 COVID-19, pandemic, knowledge, Infection, outcome, Medicine, outbreak, Patient, death, COVID-19 patients, microorganism, antibiotic, Escalation, confirmed case, Severe COVID-19 Infection, Medicines, Abstract, treat, highlight, Occurrence, caused, active against, cured, silent, hidden, claimed, the SARS-CoV-2, use of antibiotics, 【제목키워드】 COVID-19,