The convergence of the HIV and SARS-CoV-2 pandemics is an emerging field of interest. In this review, we outline the central nervous system (CNS) effects of COVID-19 in the general population and how these effects may manifest in people with HIV (PWH). We discuss the hypothetical mechanisms through which SARS-CoV-2 could impact the CNS during both the acute and recovery phases of infection and the potential selective vulnerability of PWH to these effects as a result of epidemiologic, clinical, and biologic factors. Finally, we define key research questions and considerations for the investigation of CNS sequelae of COVID-19 in PWH.
All Keywords
【저자키워드】 COVID-19, SARS-CoV-2, HIV, Central nervous system, 【초록키워드】 Infection, Factors, Pandemics, General population, CNS, mechanism, biologic, selective, Research question, Effect, hypothetical, people with HIV, 【제목키워드】 Effect, System, nervous, with HIV,
【저자키워드】 COVID-19, SARS-CoV-2, HIV, Central nervous system, 【초록키워드】 Infection, Factors, Pandemics, General population, CNS, mechanism, biologic, selective, Research question, Effect, hypothetical, people with HIV, 【제목키워드】 Effect, System, nervous, with HIV,