Aims: This study aimed to investigate the clinical courses and outcomes of diabetes mellitus patients with coronavirus disease 2019 (COVID-19) in Wuhan. Methods: This study enrolled 1,880 consecutive patients with confirmed COVID-19 in Leishenshan Hospital. We collected and analyzed their data, including demographic data, history of comorbidity, clinical symptoms, laboratory tests, chest computed tomography (CT) images, treatment options, and survival. Results: The percentages of patients with diabetes among the severe and critical COVID-19 cases were higher than those among the mild or general cases (89.2%, 10.8 vs. 0%, p = 0.001). However, patients with and without diabetes showed no difference in the follow-up period ( p = 0.993). The mortality rate in patients with or without diabetes was 2.9% ( n = 4) and 1.1% ( n = 9), respectively ( p = 0.114). Univariate and multivariate Cox regression analyses and the Kaplan-Meier curves did not show any statistically significant differences between patients with and without diabetes (all p > 0.05). Conclusions: Our study results suggested that diabetes had no effect on the prognosis of COVID-19 patients but had a negative association with their clinical courses. These results may be useful for clinicians in the management of diabetic patients with COVID-19.
【저자키워드】 Prognosis, Diabetes Mellitus, Comorbidity, Coronavirus disease 2019 (COVID-19), clinical courses, 【초록키워드】 COVID-19, Treatment, coronavirus disease, Clinical symptoms, Laboratory tests, outcome, Chest computed tomography, Clinical course, survival, management, Wuhan, Patient, Mild, mortality rate, Critical, association, Analysis, COVID-19 patient, follow-up period, clinician, COVID-19 case, no difference, demographic data, multivariate Cox regression, statistically significant difference, Kaplan-Meier curve, courses, diabetic patient, enrolled, analyzed, collected, suggested, had no, diabete, consecutive patient, patients with diabete, percentage, with COVID-19, 【제목키워드】 Wuhan, Sample,