Objective: Researching the prognostic value of myocardial enzymes in COVID-19 patients. Materials & methods: We collected 113 confirmed COVID-19 patients. The dynamic changes of CK, LDH and α-HBDH in patients were studied retrospectively, the correlation between myocardial enzyme index, clinical classification and outcome of patients and its significance to prognosis. Results: There are significant statistical differences between LDH, α-HBDH, CK and the clinical classification, and patient’s outcome. In the receiver operating characteristic curve analysis, LDH, α-HBDH and CK have a good diagnostic value for the death outcome of patients. Conclusion: LDH, α-HBDH and CK were the components of myocardial enzyme profiles, and our results found that they were significantly positively correlated with clinical classification and prognosis of COVID-19 patients. The values of LDH, α-HBDH and CK increased with the increase of the severity of admission clinical classification and the deterioration of outcome. Therefore, we propose that continuous monitoring of LDH, α-HBDH and CK indicators can warn the deterioration of COVID-19 to a certain extent, regardless of whether patients with cardiovascular diseases are combined or not, and prompt early intervention.
【저자키워드】 COVID-19, LDH, CK, prognostic evaluation, α-HBDH, 【초록키워드】 Prognosis, severity, cardiovascular disease, Intervention, outcome, continuous monitoring, Deterioration, Patient, death, correlation, characteristic, change, Admission, patients, COVID-19 patients, Analysis, Prognostic value, enzyme, diagnostic value, profiles, material, Myocardial, collected, significantly, myocardial enzyme, positively correlated, statistical difference, 【제목키워드】 COVID-19 patient, poor prognosis, myocardial enzyme,