Aim: Many factors have been speculated to explain the COVID-19 complex clinical phenotype. Due to the inconsistent data published on blood groups and COVID-19, we conducted a study on Iranian patients to further assess this association. Materials & methods: This retrospective study was conducted on data collected from confirmed COVID-19 hospitalized patients during March and December 2020 in a referral hospital for COVID-19, 5 Azar Hospital, Gorgan, north of Iran. A total of 1554 confirmed COVID-19 cases were enrolled in the study with blood group (ABO and Rh), demographic, and clinical data available. Results: Of 1554 patients, 1267 and 287 cases had recovered and deceased (due to COVID-19) outcomes, respectively. Most of the cases had O+ (29.6%), the least number had AB- (0.5%), and most of the deceased cases had O+ blood types (31.4%). Logistic regression analysis revealed that groups A- and B- had higher and groups B+, AB+, O+ and O- had lower odds of death than the A+ group. Conclusion: This study indicates that blood types may be related to the clinical outcome of COVID-19. Further studies with a large cohort for multiple people are required to validate this association.
【저자키워드】 COVID-19, SARS-CoV-2, Iran, Blood groups, ABO, Rh, 【초록키워드】 hospital, Clinical outcome, outcomes, Retrospective study, Patient, death, large cohort, group, patients, Blood, Blood Group, association, clinical phenotype, Deceased, regression analysis, Factor, Clinical data, material, MOST, confirmed COVID-19 case, enrolled, collected, required, conducted, indicate, hospitalized patient, explain, 【제목키워드】 outcome, Patient, Blood Group,