Enteritis as the only manifestation of novel coronavirus disease 2019 (COVID-19) in adolescents without features of multisystem inflammatory syndrome in children (MIS-C) or a prior history of inflammatory bowel disease (IBD) has not been described. We report two adolescent patients (a 14-year-old male and a 20-year-old pregnant female) presenting to tertiary-care centers in the United States with severe enteritis as the only manifestation of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The patients were hospitalized with acute abdominal pain and gastrointestinal (GI) bleeding, with no evidence of MIS-C, and were previously healthy with no history of IBD. The patients’ nasopharyngeal swabs were positive for SARS-CoV-2 infection by reverse transcription polymerase chain reaction (RT-PCR), and testing for other infectious etiologies was negative. Both patients received intravenous corticosteroids and recovered without short-term complications. None of the patients died. This report highlights the need for keeping a high index of suspicion for SARS-CoV-2 infection in adolescents presenting solely with gastrointestinal manifestations, in the absence of respiratory symptoms or multisystem involvement, for prompt recognition and timely management.
【초록키워드】 Corticosteroid, COVID-19, SARS-CoV-2, coronavirus, Hospitalized, SARS-COV-2 infection, children, Infection, novel coronavirus disease, abdominal pain, RT-PCR, MIS-C, Inflammatory bowel disease, Nasopharyngeal swab, management, male, female, Patient, bleeding, Manifestations, complications, reverse transcription, etiology, IBD, Evidence, pregnant, Inflammatory, intravenous, acute respiratory syndrome, syndrome, respiratory symptom, positive, Enteritis, feature, highlight, polymerase chain, described, caused, died, healthy, the patient, the United State, absence, presenting, 【제목키워드】 COVID-19, Adolescent, novel, manifestation, Enteritis, Sole,