COVID-19 is typically associated with fever and severe respiratory symptoms including dry cough and dyspnea. However, COVID-19 may also affect both central and peripheral nervous systems. To date, the incidence rate of spinal cord involvement in COVID-19 is not known and the pathogenesis is still not fully understood. We report here two female patients admitted to Assiut University Hospitals/Egypt during the period from first of July to August 10, 2020. Both presented with a positive SARS-CoV-2 polymerase chain reaction (PCR) nasopharyngeal swab, elevated serum d -dimer and ferritin levels, and bilateral ground glass appearance in a CT chest scan. The first was a 60-year-old female with acute onset of flaccid paraplegia 10 days after flu-like symptoms, in whom MRI revealed transverse myelitis. The second was a 21-year-old female with symptoms of acute quadriplegia, fever, headache, and anosmia in whom an MRI scan revealed long cervico-thoracic myelopathy. Anterior spinal artery occlusion and possibly transverse myelitis were considered as differential diagnosis of long segment myelopathy.
【저자키워드】 COVID-19, Case report, transverse myelitis, spinal cord myelopathy, anterior spinal artery occlusion, anterior spinal artery infarct, magnetic resonance image (MRI), SARC V2, 【초록키워드】 SARS-CoV-2, Pathogenesis, Symptom, headache, MRI, Anosmia, Nasopharyngeal swab, serum, PCR, Fever, Dyspnea, female, incidence rate, ground glass, university, differential diagnosis, dry cough, flu-like symptoms, ferritin levels, CT chest, d -dimer, positive, Affect, polymerase chain, elevated, female patient, Anterior, paraplegia, severe respiratory symptom, 【제목키워드】 CORD, spinal, myelopathy,