Background: During the coronavirus-19 (COVID-19) pandemic various containment strategies were employed. Their impact on individuals with neurological conditions, considered vulnerable to COVID-19 complications, remains to be determined. Objective: To investigate associations between physical activity and health-related quality of life outcomes in individuals with a neurological condition during government mandated COVID-19 restrictions. Methods: An e-survey assessing fear of COVID-19, physical activity level and health-related quality of life outcomes (functional disability and pain, anxiety and depression, loneliness, fatigue, and vitality) was distributed to individuals with a neurologically-related mobility disability living in the United Kingdom. Open-ended questions were also included to contextualize barriers and facilitators to engage in physical activity during the COVID-19 pandemic. Gamma-weighted generalized linear models and tree-structured regression models were employed to determine the associations between physical activity and health-related quality of life. Results: Of 199 responses, 69% reported performing less physical activity compared to pre-pandemic. Tree-structured regression models revealed that lower leisure-time physical activity was significantly associated ( p ≤ 0.009) with higher depression and fatigue, but lower vitality. The closure of leisure facilities and organized sport (27%) was the most commonly cited barrier to engage in physical activity, while 31% of participants mentioned concerns around their physical and mental health as a facilitator. Conclusion: Our analysis identified homogenous subgroups for depression, fatigue, and vitality based specifically on leisure-time physical activity cut points, irrespective of additional demographic or situational characteristics. Findings highlight the importance of and need to safely promote leisure-time physical activity during the COVID-19 pandemic in this at-risk population to help support health-related quality of life.
【저자키워드】 SARS-CoV-2, exercise, pandemic, mental health, Well-being, Neurological disorders, 【초록키워드】 COVID-19, Anxiety, Depression, fatigue, physical activity, COVID-19 pandemic, loneliness, outcome, COVID-19 complications, Characteristics, Regression model, Pain, Quality of life, United Kingdom, association, Analysis, Containment strategy, neurological, Generalized linear model, Support, Government, subgroup, individual, help, participant, finding, facilitator, responses, physical, highlight, significantly, reported, functional, less, determine, question, promote, conditions, homogenous, engage, organized, 【제목키워드】 COVID-19, activity, Mobility, disability, Quality, life,