Along with the propagation of COVID-19, emerging evidence reveals significant neurological manifestations in severely infected COVID-19 patients. Among these patients admitted to the intensive care unit (ICU), behavioral unresponsiveness may occur frequently, yet, there are still only a few cases reported and with rare descriptions of their motor behavior after pathological awakening. Several hypotheses regarding central lesions in these patients are conceivable. Here, we describe two acute SARS-CoV-2- infected patients who developed neurological symptoms evoking the condition of clinical cognitive motor dissociation (CMD). This diagnosis could be confirmed first by clinical observation of a dissociation between preserved cognitive abilities and lack of initial motor interaction and second, by performing 18 F- FDG PET imaging. Accurate diagnosis led to an appropriate neuro-rehabilitation regimen with long-term neuro-rehabilitation leading to an improved outcome for both patients.
【저자키워드】 COVID-19, SARS-CoV-2, pet, Neurological complications, 18F-FDG, unresponsiveness, 【초록키워드】 intensive care, Diagnosis, outcome, ICU, Patient, patients, FDG, COVID-19 patients, Evidence, Interaction, regimen, observation, lesion, cognitive, description, neurological manifestation, Neurological symptom, initial, lack, reported, occur, infected patient, reveal, hypothese, PET imaging, preserved, 【제목키워드】 Behavior, PET/CT, motor,