The Coronavirus disease 2019 (COVID-19) pandemic is still spread and has made a severe public health threat around the world. To improve disease progression, emerging Chinese herbal compounds were used in clinical practice and some agents have proven beneficial in treating COVID-19. Here, the relevant literature from basic researches to clinical application were identified and comprehensively assessed. A variety of Chinese herbal compounds have been reported to be effective in improving symptoms and outcomes in patients with COVID-19, particularly together with routine treatment strategy. The pharmacological activities were mainly attributed to the relief of clinical symptoms, inhibition of cytokine storm, and improvement of organ function. Besides, the development of novel antiviral drugs from medicinal herbs were further discussed. The updated laboratory and clinical studies provided the evidence of Chinese herbal compounds such as Lianhua Qingwen prescription, Shufeng Jiedu prescription, and Qingfei Paidu Tang for the relief of COVID-19. However, both of the randomized controlled trials and real world researches need to be done for supporting the evidence including the efficacy and safety in fighting COVID-19.
【저자키워드】 COVID-19, SARS-CoV-2, coronavirus, Chinese herbal compounds, 【초록키워드】 Randomized controlled trial, Treatment, Coronavirus disease 2019, Cytokine storm, pandemic, Clinical symptoms, Symptom, outcome, Laboratory, activity, Spread, Disease progression, Efficacy and safety, Clinical practice, clinical study, Evidence, Chinese, treating COVID-19, organ function, public health threat, pharmacological, effective, IMPROVE, reported, provided, were used, variety, herbal compound, novel antiviral drug, patients with COVID-19, 【제목키워드】 coronavirus disease, Laboratory, clinical study, potential mechanism, Chinese, herbal compound,