We present a unique case of a male veteran with a history of Castleman disease, presenting with multiple arterial and venous vascular thromboses in the setting of recent Coronavirus (COVID-19)-disease diagnosis. We explore this patient’s morbidity related to thrombotic complications of his COVID-19 diagnosis that were potentially avoidable with a comprehensive outpatient evaluation of his risk for thrombosis, as well as the initiation of anticoagulation and/or antiplatelet therapy given his high risk. Our case highlights the need for a standardized clinical workup of patients in the outpatient setting for risk assessment of vascular thrombosis associated with COVID-19 infection to direct medical management, in order to minimize adverse outcomes, complications requiring inpatient admission, and the need for additional yet limited medical resources and interventions. We propose a minimum of low-dose aspirin 81 mg daily as a reasonable approach for outpatient clinicians to consider, based on their best clinical judgement, when managing mild COVID-19, while other options, such as novel oral anticoagulants, are undergoing further investigation.
【저자키워드】 COVID-19, anticoagulation, Renal Infarction, Pulmonary emboli, spleen infarct, arterial thrombi, Castleman disease, 【초록키워드】 therapy, thrombosis, Infection, Diagnosis, risk, adverse outcomes, management, low-dose, morbidity, male, Patient, COVID-19 diagnosis, Complication, Mild, Aspirin, disease, antiplatelet, high risk, Oral anticoagulants, Vascular, clinician, inpatient admission, vascular thrombosis, approach, venous, thrombotic complication, medical resource, highlight, unique, presenting, with COVID-19, 【제목키워드】 renal,