Purpose To determine the relationship between the genotypes of the TaqI polymorphism of VDR gene and the clinical forms of COVID-19 in Cuban patients. Methods TaqI polymorphism was determined by the PCR in 104 Cuban patients, who suffered different clinical forms of COVID-19. Results There was a greater possibility of presenting symptomatic forms [OR = 2.081, 95% CI: 0.243–17.842], even severe [OR = 1.200, 95% CI: 0.217–6.638], related to the tt genotype. Conclusion There are signs of association between the risk of developing COVID-19 and the genotypes of the TaqI polymorphism of the VDR gene in the studied Cuban patients.
All Keywords
【저자키워드】 COVID-19, Vitamin D, alleles, receptor, Genetic polymorphism, Cuba, 【초록키워드】 polymorphism, risk, PCR, symptomatic, Genotype, VDR, patients, association, Result, greater, form, was determined, determine, suffered, presenting, clinical form, 【제목키워드】 polymorphism, Patient, VDR,
【저자키워드】 COVID-19, Vitamin D, alleles, receptor, Genetic polymorphism, Cuba, 【초록키워드】 polymorphism, risk, PCR, symptomatic, Genotype, VDR, patients, association, Result, greater, form, was determined, determine, suffered, presenting, clinical form, 【제목키워드】 polymorphism, Patient, VDR,