Thrombotic complications and coagulopathy frequently occur in COVID-19. However, the characteristics of COVID-19-associated coagulopathy (CAC) are distinct from those seen with bacterial sepsis-induced coagulopathy (SIC) and disseminated intravascular coagulation (DIC), with CAC usually showing increased D-dimer and fibrinogen levels but initially minimal abnormalities in prothrombin time and platelet count. Venous thromboembolism and arterial thrombosis are more frequent in CAC compared to SIC/DIC. Clinical and laboratory features of CAC overlap somewhat with a hemophagocytic syndrome, antiphospholipid syndrome, and thrombotic microangiopathy. We summarize the key characteristics of representative coagulopathies, discussing similarities and differences so as to define the unique character of CAC.
【저자키워드】 COVID-19, Coagulopathy, Antiphospholipid syndrome, Disseminated intravascular coagulation, thrombotic microangiopathy, hemophagocytic syndrome, 【초록키워드】 thrombosis, D-dimer, Characteristics, clinical, Thromboembolism, Platelet, Complication, Coagulopathies, Bacterial, similarity, Prothrombin time, overlap, syndrome, thrombotic, abnormality, sepsis-induced coagulopathy, occur, unique, to define, fibrinogen level, laboratory feature, 【제목키워드】 Characteristics, unique,