Abstract Background Currently, the epidemic of coronavirus disease 2019 (COVID‐19) has begun to spread worldwide. We aim to explore reliable evidence for the diagnosis and treatment of the COVID‐19 by analyzing all the published studies by Chinese scholars on the clinical and imaging features in novel coronavirus pneumonia caused by SARS‐CoV‐2. Methods We searched five medical databases including two Chinese and three English databases for all published articles on COVID‐19 since the outbreak. A random‐effects model was designed, and the imaging and clinical data from all studies were collected for meta‐analysis. Results Overall, 31 articles and 46 959 patients were included, including 10 English articles and 21 Chinese articles. The results of meta‐analysis showed that the most common clinical manifestations were fever (87.3%; 0.838‐0.909), cough (58.1%; 0.502‐0.660), dyspnea (38.3%; 0.246‐0.520), muscle soreness or fatigue (35.5%; 0.253‐0.456), and chest distress (31.2%; −0.024 to 0.648). The main imaging findings were bilateral pneumonia (75.7%; 0.639‐0.871) and ground‐glass opacification (69.9%; 0.602‐0.796). Among the patients, the incidence that required intensive care unit (ICU) was (29.3%; 0.190‐0.395), the incidence with acute respiratory distress syndrome was (28.8%; 0.147‐0.429), the incidence with multiple organ dysfunction syndrome was (8.5%; −0.008 to 0.179), and the case fatality rate of patients with COVID‐19 was (6.8%; 0.044‐0.093). Conclusion COVID‐19 is a new clinical infectious disease that mainly causes bilateral pneumonia and lung function deteriorates rapidly. Nearly a third of patients need to be admitted to the ICU, and patients are likely to present respiratory failure or even death. Research Highlights In 2019, coronavirus disease (covid‐19) has started to spread globally. How to quickly identify influenza and covid‐19 is the key to ensure timely and effective treatment. The fever and cough were the main clinical manifestations of the patients with novel coronavirus pneumonia in China, and the main complications are respiratory failure, acute respiratory distress syndrome. Nearly a third of patients need to be admitted to the ICU, and some patients are likely to cause respiratory failure or even death.
【저자키워드】 SARS‐CoV‐2, Clinical features, 2019 novel coronavirus pneumonia, imaging finding, 【초록키워드】 Treatment, coronavirus disease, Respiratory failure, intensive care, fatigue, Pneumonia, Influenza, Diagnosis, Infectious disease, cough, database, ICU, Novel coronavirus, COVID‐19, SARS‐CoV‐2, Spread, China, outbreak, Chest, Fever, Lung function, Dyspnea, Patient, death, Complication, incidence, patients, multiple organ dysfunction, acute respiratory distress, Evidence, distress, clinical manifestation, Clinical data, syndrome, Chinese, Fatality rate, bilateral pneumonia, article, FIVE, articles, feature, effective, English, the epidemic, Result, identify, collected, caused, the patient, required, searched, cause, deteriorate, 【제목키워드】 systematic review, 2019 novel coronavirus, imaging, Patient, clinical feature,