Abstract
Background: Our objective was to safely and remotely assess longitudinal SARS-CoV-2 seroprevalence in at-risk health care workers at the onset of the epidemic.
Methods: Self-administered serologic testing was performed every 30 days up to 5 times using a point-of-care, lateral flow SARS-CoV-2 nucleocapsid IgG immunoassay in a cohort of at-risk health care workers (n = 339) and lower-risk controls (n = 100).
Results: Subjects were enrolled between 4/14/20-5/6/20 and most were clinicians (41%) or nurses (27%). Of 20 subjects who reported confirmed SARS-CoV-2 infection prior to (n = 5, 1%) or during the study (n = 15, 3%), half (10/20) were seropositive. Five additional subjects were seropositive and did not report documented infection. Estimated infection rates in health care workers did not differ from concurrent community rates.
Conclusions: This remotely conducted, contact-free study did not identify serologic evidence of widespread occupational SARS-CoV-2 infection in health care workers.
【초록키워드】 IgG, SARS-COV-2 infection, health care workers, Infection, lateral flow, immunoassay, point-of-care, Cohort, SARS-CoV-2 seroprevalence, Control, Community, Health care worker, infection rate, seropositive, serologic testing, Evidence, Nurse, clinician, subject, SARS-CoV-2 nucleocapsid, widespread, the epidemic, enrolled, not differ, identify, reported, conducted, was performed, Estimated, 【제목키워드】 SARS-CoV-2 seroprevalence, Health care worker,