Abstract
A 52-year-old man with mantle cell lymphoma treated with bendamustine and rituximab developed prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Despite elevated titers of anti-spike IgG antibody, protracted pancytopenia persisted for more than six months. Finally, the anti-SARS CoV-2 vaccine, BNT162b2, was administered, which improved his blood cell count and eliminated the virus. The increased anti-spike IgG titer and lymphocyte count after vaccination suggested that both humoral and cellular immunity acted in coordination to eliminate the virus.
Keywords: SARS-CoV-2; anti-spike IgG; bendamustine; cellular immunity; prolonged infection; vaccine.
All Keywords
【저자키워드】 SARS-CoV-2, Vaccine, anti-Spike IgG, cellular immunity, Bendamustine, Prolonged infection, 【초록키워드】 Vaccine, coronavirus, vaccination, antibody, Infection, virus, BNT162b2, Lymphocyte count, lymphoma, Anti-spike, cellular, blood cell count, humoral, acute respiratory syndrome, Administered, elevated, treated, suggested, eliminated, mantle cell, 【제목키워드】 Elimination, BNT162b2, Prolonged,
【저자키워드】 SARS-CoV-2, Vaccine, anti-Spike IgG, cellular immunity, Bendamustine, Prolonged infection, 【초록키워드】 Vaccine, coronavirus, vaccination, antibody, Infection, virus, BNT162b2, Lymphocyte count, lymphoma, Anti-spike, cellular, blood cell count, humoral, acute respiratory syndrome, Administered, elevated, treated, suggested, eliminated, mantle cell, 【제목키워드】 Elimination, BNT162b2, Prolonged,