Abstract
A forty-seven-year-old recipient in late period after kidney transplantation with chronic estimated glomerular filtration rate (eGFR) 30 mL/min/1.73 m 2 , fully vaccinated against COVID-19 was diagnosed with SARS-CoV-2 infection in November 2021. After an initially mild course of the disease, he developed multiorgan failure requiring periodic respiratory and dialysis therapy. Covid-19 disease was complicated by multiple infections such Clostridioides difficile infection, Streptococcus epidermidis bacteriemia, Klebsiella pneumoniae and Candida glabrata urinary tract disease, cytomegalovirus infection and oral candidiasis. In a short period, he was readmitted to the hospital twice with recurrent Klebsiella pneumoniae urosepsis. One of those hospitalizations was also complicated by another COVID-19 infection that was confirmed with non-reactive neutralizing antibody. Due to severe infections the patient required individualized modification of immunotherapy; however, due to their recurrence it was finally decided to be discontinued. The patient was also reintroduced to hemodialysis therapy and no infections occurred since then.
Keywords: SARS-CoV-2; kidney transplantation; multi-pathogenic infections.
【저자키워드】 SARS-CoV-2, Kidney transplantation, multi-pathogenic infections., 【초록키워드】 neutralizing antibody, Severe infection, therapy, Hospitalization, SARS-COV-2 infection, hospital, Infection, oral candidiasis, dialysis, kidney, infections, Hemodialysis, COVID-19 infection, Patient, Mild, Urinary tract, disease, glomerular filtration rate, Candida, Klebsiella pneumoniae, Clostridioides difficile infection, multiorgan failure, Modification, Streptococcus, Course, occurred, the patient, diagnosed, the disease, required, vaccinated against COVID-19, 【제목키워드】 Transplant, Complication, recipient, Multiple,