Abstract
We detected a highly divergent SARS-CoV-2 Alpha variant in an immunocompromised person several months after the latest detection of the Alpha variant in the Netherlands. The patient was infected for 42 weeks despite several treatment regimens and disappearance of most clinical symptoms. We identified several potential immune escape mutations in the spike protein.
Keywords: Alpha variant; COVID-19; SARS-CoV-2; coronavirus disease; immunocompromised; respiratory infections; severe acute respiratory syndrome coronavirus 2; the Netherlands; variants; virus evolution; viruses; zoonoses.
All Keywords
【저자키워드】 COVID-19, coronavirus disease, severe acute respiratory syndrome coronavirus 2, viruses, respiratory infections, zoonoses, SARS-CoV-2, Virus evolution, variants, Immunocompromised, Alpha variant, The Netherlands, 【초록키워드】 zoonoses, coronavirus, Clinical symptoms, virus, immune escape mutation, Patient, Netherlands, acute respiratory syndrome, treatment regimen, the spike protein, 【제목키워드】 Person,
【저자키워드】 COVID-19, coronavirus disease, severe acute respiratory syndrome coronavirus 2, viruses, respiratory infections, zoonoses, SARS-CoV-2, Virus evolution, variants, Immunocompromised, Alpha variant, The Netherlands, 【초록키워드】 zoonoses, coronavirus, Clinical symptoms, virus, immune escape mutation, Patient, Netherlands, acute respiratory syndrome, treatment regimen, the spike protein, 【제목키워드】 Person,