The use of pre-procedural rinses has been investigated to reduce the number of viral particles and bacteria in aerosols, potentially decreasing the risk of cross-infection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during medical and dental procedures. This review aims to confirm whether there is evidence in the literature describing a reduction in salivary load of SARS-CoV-2 when povidone-iodine (PVP-I) is used as a pre-intervention mouthwash. An search of the MEDLINE, Embase, SCOPUS, and the Cochrane library databases was conducted. The criteria used followed the PRISMA ® Statement guidelines. Randomized controlled trials investigating the reduction of salivary load of SARS-CoV-2 using PVP-I were included. Ultimately, four articles were included that met the established criteria. According to the current evidence, PVP-I is effective against SARS-CoV-2 in saliva and could be implemented as a rinse before interventions to decrease the risk of cross-infection in healthcare settings.
【저자키워드】 COVID-19, SARS-CoV-2, Aerosols, mouthwashes, mouthrinse, chlorhexidine, povidone-iodine, cetylpiridinium chloride, hydrogen peroxide, colony-forming units, 【초록키워드】 Saliva, coronavirus, Randomized controlled trials, risk, Intervention, severe acute respiratory syndrome Coronavirus, database, Aerosols, Viral, healthcare, Controlled trial, Bacteria, povidone-iodine, respiratory, Evidence, Viral particles, Cross-infection, criteria, dental procedures, reduction, acute respiratory syndrome, Povidone-Iodine (PVP-I, acute respiratory syndrome coronavirus, acute respiratory syndrome coronavirus 2, article, viral particle, povidone, povidone-iodine (PVP-I), salivary, effective, decrease, investigated, conducted, reduce, reduction in, the MEDLINE, 【제목키워드】 review, Mouthwash, povidone-iodine, load, Controlled,