As a response to the coronavirus disease 2019 (COVID-19) pandemic, Vietnam enforced strict quarantine, contact tracing and physical distancing policies resulting in one of the lowest numbers of individuals infected with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) globally. This study aimed to determine the prevalence of SARS-CoV-2 antibody positivity among high-risk populations in Vietnam. A prevalence survey was undertaken within four communities in Vietnam, where at least two COVID-19 cases had been confirmed. Participants were classified according to the location of exposure: household contacts, close contacts, community members, and healthcare workers (HCWs) responsible for treating COVID-19 cases. Participants completed a baseline questionnaire and SARS-CoV-2 IgG antibodies were quantified using a commercial assay. A total of 3049 community members and 149 health care workers consented to the study. Among 13 individuals who were seropositive (0.4%), five household contacts (5/27, 18.5%), one close contact (1/53, 1.9%), and seven community members (7/2954, 0.2%) had detectable SARS-CoV-2 antibodies. All HCWs were negative for SARS-CoV-2 antibodies. Participants were tested a median of 15.1 (interquartile range from 14.9 to 15.2) weeks after exposure. Our study found a low prevalence of SARS-CoV-2 antibodies in high-risk communities and healthcare workers in communities in Vietnam with known COVID-19 cases.
【저자키워드】 COVID-19, SARS-CoV-2, Seroprevalence, Vietnam, 【초록키워드】 coronavirus disease, Coronavirus disease 2019, pandemic, Health care, Healthcare workers, quarantine, Contact tracing, healthcare worker, Prevalence, Severe acute respiratory syndrome, SARS-CoV-2 antibodies, SARS-CoV-2 antibody, IgG antibodies, HCWs, SARS-CoV-2 IgG antibody, Community, Health care worker, location, household contact, respiratory, questionnaire, seropositive, severe acute respiratory syndrome-coronavirus-2, high-risk population, household contacts, close contact, COVID-19 cases, HCW, interquartile range, COVID-19 case, individual, SARS-CoV-2 IgG antibodies, participant, treating COVID-19, FIVE, Seven, lowest, responsible, resulting, tested, detectable, median, determine, quantified, baseline, physical distancing policy, 【제목키워드】 Population,