Highly Pathogenic Reassortant Avian Influenza A(H5N1) Virus Clade 2.3.2.1a in Poultry, Bhutan

Published on
Journal: Emerging Infectious Diseases
[저자] Atanaska Marinova-Petkova, John Franks, Sangay Tenzin, Narapati Dahal, Kinzang Dukpa, Jambay Dorjee, Mohammed M. Feeroz, Jerold E. Rehg, Subrata Barman, Scott Krauss, Pamela McKenzie, Richard J. Webby, Robert G. Webster
[Category] Fulltext, 조류인플루엔자,
PMC URL    Pubmed URL    [DOI] 10.3201/eid2212.160611    
[Source] PMC

Highly pathogenic avian influenza A(H5N1), clade 2.3.2.1a, with an H9-like polymerase basic protein 1 gene, isolated in Bhutan in 2012, replicated faster in vitro than its H5N1 parental genotype and was transmitted more efficiently in a chicken model. These properties likely help limit/eradicate outbreaks, combined with strict control measures.

All Keywords
【저자키워드】 viruses, zoonoses, Influenza, Transmission, Influenza virus, outbreak, Bhutan, Indian subcontinent, Avian Influenza, reassortant, Highly Pathogenic Avian Influenza H5N1, clade 2.3.2.1a, ferret model: respiratory diseases,