Reverse transcriptase polymerase chain reaction (RT-PCR) negative results in the upper respiratory tract represent a major concern for the clinical management of coronavirus disease 2019 (COVID-19) patients. Herein, we report the case of a 43-years-old man with a strong clinical suspicion of COVID-19, who resulted in being negative to multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RT-PCR tests performed on different oropharyngeal and nasopharyngeal swabs, despite serology having confirmed the presence of SARS-CoV-2 IgM. The patient underwent a chest computed tomography (CT) that showed typical imaging findings of COVID-19 pneumonia. The presence of viral SARS-CoV-2 was confirmed only by performing a SARS-CoV-2 RT-PCR test on stool. Performing of SARS-CoV-2 RT-PCR test on fecal samples can be a rapid and useful approach to confirm COVID-19 diagnosis in cases where there is an apparent discrepancy between COVID-19 clinical symptoms coupled with chest CT and SARS-CoV-2 RT-PCR tests’ results on samples from the upper respiratory tract.
【저자키워드】 COVID-19, SARS-CoV-2, RT-PCR, Computed tomography, Viral pneumonia, Nasopharyngeal swab, oropharyngeal swab, Chest, feces, fecal swab, 【초록키워드】 coronavirus disease, Coronavirus disease 2019, coronavirus, COVID-19 pneumonia, Clinical symptoms, Pneumonia, serology, RT-PCR, Computed tomography, Chest computed tomography, polymerase chain reaction, Stool, Viral, Reverse transcriptase polymerase chain reaction, Chest CT, nasopharyngeal swabs, Patient, COVID-19 diagnosis, Fecal sample, Clinical management, Oropharyngeal, SARS-CoV-2 RT-PCR, respiratory, PCR test, upper respiratory tract, patients, SARS-CoV-2 IgM, RT-PCR test, reverse transcriptase, Chain Reaction, RT-PCR tests, acute respiratory syndrome, acute respiratory syndrome coronavirus, acute respiratory syndrome coronavirus 2, clinical symptom, clinical suspicion, SARS-CoV-2 RT-PCR test, discrepancy, fecal samples, Performing, approach, polymerase chain, performed, 【제목키워드】 COVID-19 pneumonia, Test, detection, Nasopharyngeal swab, SARS-CoV-2 RT-PCR, finding, Multiple, negative, Sample, Typical,