Background and Objectives : This study aimed to evaluate the relationship between mortality and cardiac laboratory findings in patients who were hospitalized after a positive PCR for COVID-19 infection. Materials and Methods : This study included patients who were admitted to or referred to the hospital between 20 March and 20 June 2020, diagnosed with COVID-19 via a positive RT-PCR from nasal and pharyngeal swab samples. The troponin I level was measured from each patient. Medical records of patients were retrospectively reviewed and analyzed. Results : A hundred and five patients who were diagnosed with COVID-19 and hospitalized, or who died in the hospital due to COVID-19, were included in this study. There was a statistically significant difference between the troponin I high and low level groups in terms of age (years), BMI, shortness of breath (SB), oxygen saturation (%), hypertension, length of stay in the ICU; and for mortality, C-reactive protein, the neutrophil-to-lymphocyte ratio, hemoglobin, lactate dehydrogenase, ferritin, D-dimer, creatine kinase-MB, prothrombin time, calcium, and 25-hydroxy vitamin 25(OH)D3 (all p < 0.05). In the logistic analyses, a significant association was noted between troponin I and the adjusted risk of mortality. A ROC curve analysis identified troponin I values > 7.8 pg/mL as an effective cut-off point in mortality for patients with COVID-19. A troponin I value of higher than 7.8 pg/mL yielded a sensitivity of 78% and a specificity of 86%. Conclusions : The hospital mortality rate was higher among patients diagnosed with COVID-19 accompanied by troponin levels higher than 7.8 pg/mL. Therefore, in patients diagnosed with COVID-19, elevated troponin I levels >7.8 pg/mL can be considered an independent risk factor for mortality.
【저자키워드】 Coronavirus disease 2019, Mortality, novel, cardiac damage, troponin I, 【초록키워드】 COVID-19, Hospitalized, creatine, hospital, neutrophil, C-reactive protein, risk, D-dimer, troponin, ferritin, oxygen, nasal, hypertension, lactate dehydrogenase, Laboratory, laboratory findings, Neutrophil-to-lymphocyte ratio, lymphocyte, oxygen saturation, sensitivity, specificity, COVID-19 infection, Patient, age, hemoglobin, creatine kinase, BMI, troponin I, group, calcium, association, Creatine kinase-MB, positive RT-PCR, Lactate, Analysis, ROC Curve, Prothrombin time, referred to, medical records, medical record, cut-off point, Shortness of breath, Pharyngeal swab, Logistic, statistically significant difference, troponin levels, independent risk factor, material, cut-off, positive PCR, hospital mortality rate, objective, FIVE, effective, Result, was measured, analyzed, evaluate, died, elevated, adjusted, analyses, accompanied, diagnosed with COVID-19, patients with COVID-19, troponin level, 【제목키워드】 COVID-19, troponin I, assessment, relationship, Level,