Abstract Objective To deal with COVID‐19, various countries have made many efforts, including the research and development of vaccines. The purpose of this manuscript was to summarize the development, application, and problems of COVID‐19 vaccines. Methods This article reviewed the existing literature to see the development of the COVID‐19 vaccine. Results We found that different types of vaccines had their own advantages and disadvantages. At the same time, the side effects of the vaccine, the dose of vaccination, the evaluation of the efficacy, and the application of the vaccine were all things worth studying. Conclusion The successful development of the COVID‐19 vaccine concerns almost all countries and people in the world. We must do an excellent job of researching the immunogenicity and immune reactivity of the vaccines. We hope this review can help colleagues at home and abroad. We reviewed the mechanism and types of COVID‐19 vaccines through the literature. At the same time, we found some existing problems in vaccines research, such as injection dosage, adverse reactions, efficacy evaluation and vaccine application. An excellent job must be performed to research the immunogenicity and immune reactivity of the COVID‐19 vaccines.
【저자키워드】 COVID‐19, Vaccine, Thoughts, application, types, 【초록키워드】 Efficacy, vaccination, immunogenicity, Vaccines, research and development, immune, COVID‐19, Adverse reactions, Research, Side effects, mechanism, Disadvantages, dose, immune reactivity, Side effect, dose of vaccination, problems, dosage, help, injection, problem, manuscript, objective, country, Result, performed, reactivity, the vaccine, 【제목키워드】 COVID‐19,